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This is an analysis of the journal article “Patients with fibromyalgia benefit from aerobic endurance exercise” by Meiworm, Jakob, et al., (2000)

[[Category:]]==Background== Fibromyalgia (FM) is a chronic condition characterised by altered pain processing, called central sensitization. FM affects tendons, muscles and ligaments resulting in widespread and persistent musculoskeletal pain “myalgia” and tender points (TP) around the body [3]. FM often co-exists with other conditions, including chronic headaches, jaw and facial pain; irritable bowel syndrome; chronic fatigue syndrome; sleep disturbances; anxiety and depression. Despite extensive research, scientists have not yet discovered a single cause of FM. It is suggested that various physical and/or psychological factors as well as certain infections may play a role in developing FM. In recent decade, genetic basis have been proposed as a key cause for FM, with some studies reporting high familial predispositions. . The main goal in treating FM is to reduce the major symptoms of the condition and should include a multiple approaches: As FM patients associate physical activity with worsening of the symptoms it is of paramount importance to encourage them to engage in a graded cardiovascular (CV) program. CV activities, such as swimming, biking, or walking can reduce painful symptoms and decrease the number of TP.
 * patient education – sleep hygiene, role of various stressors, prognosis, reassurance that FM is real
 * medications
 * nonpharmaceutical interventions (exercise)

Where Is This Research From
The experiment was conducted at the University Hospitals in Freiburg, Germany. Various departments, Division of Rheumatology and Clinical immunology, Division of Rehabilitative and Preventive Sports Medicine, and Department of Medicine anticipated in conjunction. The article was published in Clinical Rheumatology.

What Kind Of Research Was This
The research team investigated whether the aerobic endurance exercise might improve FM symptoms. In this study participants diagnosed with FM who engaged in a exercise program for 12 weeks were compared with a control group.

What Did The Research Involve
Out 76 patients diagnosed with FM in the hospital’s reumathology clinic, 31 (29F, 2M) agreed to take part in the study. 27 participants finished the study. Prior to and after the study participants were screened for several factors:
 * pain threshold
 * negative TPs with a Fischer dolorimeter
 * subjective pain, rated on a visual analogue scale
 * spiroergometric evaluation with the analysis of breathing gases and lactic acid concentration
 * ECG recordings

Over three months patients anticipated in a simple self-managed domestic training program: The control group continued their normal life.
 * two to three, 20-30 minute long, training sessions per week, without intermittent resting
 * at moderate intensity, 50% VO2 max,
 * participants could choose their discipline from cycling, jogging/walking, swimming
 * during the first 6 weeks, intensity was increased every fortnight by increasing the duration or frequency of the sessions

Results
The training group reported a decrease in the average number of positive TPs, and in subjective pain as compared to the control group. These findings are similar to a number of other studies investigating the link of aerobic exercise and reduction in painful symptoms in FM

Conclusion and Implications
Even though the findings report similar outcomes to a number of other research, the paper is not without faults. The very small sample group, n=27,, and reliance on self-reported data make the results statistically insignificant. There was no comparison to a pharmaceutical form of FM treatment. Additionally, the research lacks analysis in regards to a wide range of symptoms, i.e. sleep disturbance, mental disorders, which greatly aggravate symptoms of FM. The authors clearly state that aerobic physical activity is effective in alleviating pain in FM patients.

Further Readings
For further information regarding the fibromyalgia; click on the links below.
 * National Fibromyalgia Research Association http.www.nfra.net/
 * National Fibromyalgia Association http://www.fmaware.org/
 * Fibromyalgia and Chronic Fatigue Syndrome Forum https://www.verywell.com/fibromyalgia-and-chronic-fatigue-4014724