Talk:Structural Biochemistry

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Orphaned pages

 * Structural Biochemistry/Bacteria
 * Structural Biochemistry/Carbohydrates/Carbohydrates and Proteins/proteoglycans
 * Structural Biochemistry/Catalytic Strategies
 * Structural Biochemistry/Catalytic Strategies/General Acid-Base Catalysis
 * Structural Biochemistry/Cell Signaling Pathways/Circulatory Systems
 * Structural Biochemistry/Chromatography
 * Structural Biochemistry/Enzyme/Catalytic Principles
 * Structural Biochemistry/Enzyme/Characteritics of enzyme
 * Structural Biochemistry/Enzyme/Pre-steady state
 * Structural Biochemistry/Enzyme/Specificity
 * Structural Biochemistry/Enzyme/Substrate specificity
 * Structural Biochemistry/Enzyme/steady state
 * Structural Biochemistry/Enzyme Catalytic Mechanism
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Enzyme Classification
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Enzyme Classification/Hydrolases
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Enzyme Classification/Isomerases
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Enzyme Classification/Ligases
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Enzyme Classification/Lyases
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Enzyme Classification/Oxidoreductases
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Enzyme Classification/Transferases
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Introduction
 * Structural Biochemistry/Enzyme Catalytic Mechanism/Membrane Protein
 * Structural Biochemistry/Eukaryotes and Prokaryotes
 * Structural Biochemistry/Genetic code/Genome Sequencing
 * Structural Biochemistry/Higher Organism Recombination
 * Structural Biochemistry/MAOIs
 * Structural Biochemistry/Molecular Moldeling/Molecular Docking
 * Structural Biochemistry/Nucleic Acid/DNA/Watson and Crick
 * Structural Biochemistry/Nucleic Acid/RNA/RNA modification/RNA Splicing
 * Structural Biochemistry/Organic Chemistry/Types of Marcomolecules
 * Structural Biochemistry/Phenylhydrazine
 * Structural Biochemistry/Protein function/Additional Globins
 * Structural Biochemistry/Protein function/Binding Sites/Cooperativity/Allosterism
 * Structural Biochemistry/Protein function/Concerted Model
 * Structural Biochemistry/Protein function/Heme group/Globins
 * Structural Biochemistry/Protein function/Heme group/Hemoglobin/Association and Dissociation Constant
 * Structural Biochemistry/Protein function/Interferon
 * Structural Biochemistry/Proteins/Cutting Enzymes
 * Structural Biochemistry/Proteins/Introduction
 * Structural Biochemistry/Proteins/Posttranslational Modification of Protein
 * Structural Biochemistry/Proteins/Protein O-GlcNAcylation by O-linked β-N-acetylglucosamine
 * Structural Biochemistry/Proteins/Purification/Ion-Exchanged chromatography
 * Structural Biochemistry/Proteins/Purification/TEST
 * Structural Biochemistry/The activities of the cloning enzymes
 * Structural Biochemistry/Viruses and SLiMs Interaction/Introduction
 * Structural Biochemistry/Viruses and SLiMs Interaction/Viral Pathways/Utilizing Cellular Transport
 * Structural Biochemistry/Viruses and SLiMs Interaction/ Viral Pathways/ Manipulating Signal Transduction
 * Structural Biochemistry/Intrinsically Disordered Proteins: 10-year recap/Introduction
 * Structural Biochemistry/Intrinsically Disordered Proteins: 10-year recap/Importance and Evidence of Disorder
 * Structural Biochemistry/Intrinsically Disordered Proteins: 10-year recap/Functional modes of disordered proteins
 * Structural Biochemistry/Intrinsically Disordered Proteins: 10-year recap/Structural Disorder in Disease
 * Structural Biochemistry/Intrinsically Disordered Proteins: 10-year recap/Conclusion

These are not linked to by this book. Please mark them for deletion with, link to them, or merge them into another page and mark them with. – Adrignola talk 00:45, 12 July 2010 (UTC)

Class Project
This book appears to be a class project by students at University of California, San Diego (UCSD). The department and course details are unidentified so far. Recent Runes (discuss • contribs) 20:41, 28 October 2011 (UTC)

Book Layout has to improve
This book is a monster book and the amount of work that has undergone is extraordinary and it shows. I feel though that the book is very very large and the layout of the book has to improve. I think we have to make different pages for each subject/chapter and remove the subpages from the front page (for instance, in the 'medicine & drug design' section we can move all the listed drugs in the 'medicine & drug design' page rather than having such a long list in the front page). We can do the same for the other subjects/chapters. It is definately one of the largest books in here and it is very well written but we have to make it like a book not like an encyclopedic-index book.

For example:

Table of contents?!: *Structural Biochemistry in relation to other sciences **Physics **Chemistry **Biology ***Evolution ***The cell ***Genetics ***Biology of Cancer **Medicine and Drug Design **Neuroscience **Systems Biology **Bioinformatics **Molecular Modeling *Water *Proteins *Carbohydrates *Lipids *Nucleic Acids *Catalysis

All subsections will appear in the corresponding chapters/sections.

What do you think? U1012738 (discuss • contribs) 18:08, 1 December 2012 (UTC)

Addition to vitamin C
Vitamin C's name was given to this molecule in early days. Around 1920, Casimir Funk had introduced the term Vitamin C that is necessary and one of the nutritional factor for a pathological state known as scurvy and at time the nature of the active molecule was still unknown.

Biochemical role of Vitamin C It was said that l-lguolonolactone oxidase which is the last enzyme in ASC biosynthetic pathway made primates primates(including humans), geinea pigs and a few other animal species unable to synthesize ASC. Loss of ASC synthesis could have increased the rate of mutation and consequent change in genetic variablity which might have led into evolution. Many authors suggested that the dietary intake of vitamin C present in fruit and vegetables was enough to compensate for missing or less of synthesis. Also hydrogen peroxide is generated in reaction catalyzed by l-guolonolactone oxi-dase. Scurvy is a pathological state caused by ASC deficiency. Both ASC deficiency and low expression of prolyl hydroxylase due to inherited defects or gene manipulation, converge to the same result. Collagen being the most abundant protein in animals, consumes large ASC amounts for hydroxylation conceivably, which leads into explaining why collagen malfunctioning is the most evident sign of scurvy. It's not just this, ASC and oxidized form dehydroascorbate are protein folding in the endoplasmic reticulum, have deficiency affects. Carnitine is an essential metabolite having an indispensable role in energy metabolism. ASC deficiency also affects carnitine synthesis.