Talk:Biochemistry/pKa values

M vs. mol*dm-3
I changed the mol*dm-3 to M (molar or mol/L). Which is by far more commonly used and likely to be more easily understood by those that can remember high school level chemistry. Hichris (talk) 18:57, 18 February 2008 (UTC)

Reference
"Due to the amphipathic nature of amino acids - which are the monomer building blocks of all proteins, physiological conditions are always considered to be buffered, which plays a major role in the conformations and reactivities of substrates in the cell's liquid interior, its cytosol.

A very small (which would include a large negative value) pKa indicates a very strong acid. A pKa value between 4 and 5 is the most common range for organic acid compounds."


 * Does anyone have a reference for the above? Amino acids are amphipathetic, but I do not recall them being a major player as buffers in the cytosol - in any case they have a low and high pKa not a neutral pKa.


 * I'm also not sure about the 4-5 pKa range as most common, it may be I just haven't heard that before. Hichris (talk) 19:05, 18 February 2008 (UTC)