Radiation Oncology/RTOG Trials/0319

RTOG 03-19 (Breast)
 * Title: A Phase I/II Trial to Evaluate 3D-CRT Confined to the Region of the Lumpectomy Cavity for Stage I and II Breast Carcinoma
 * Objective:
 * Protocol:
 * 38.5 Gy Total/10 fractions (3.85 Gy per fraction), 2 fractions/day (separated by 6 hours), Given in 5 consecutive working days
 * Radiotherapy should begin within eight weeks of surgery (If chemotherapy is given first, RT begins 2 weeks after the last cycle of chemotherapy)
 * Eligibility:
 * Invasive pathology; AJCC Stage I-II; single focus
 * Negative surgical margin; up to 3 LN+
 * Enrollment Target: 46 patients
 * Activation: August 15, 2003
 * Closed: April 30, 2004