Radiation Oncology/Palliation/Brain Metastases/Guidelines

Brain Metastases Official Guidelines

National Comprehensive Cancer Network (NCCN)
 * CNS Cancers

American College of Radiology (ACR)
 * Pre-Irradiation Evaluation of Brain Metastases
 * Single Brain Metastasis
 * Multiple Brain Metastasis
 * 2009 PMID 19857783 -- "American College of Radiology appropriateness criteria on multiple brain metastases." (Videtic GM, Int J Radiat Oncol Biol Phys. 2009 Nov 15;75(4):961-5.)
 * Follow up and Retreatment of Brain Metastases

American Association of Neurologic Surgeons (AANS) / Congress of Neurologic Surgeons (CNS)
 * Steroids; 2010 PMID 19957014 -- "The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline." (Ryken TC, J Neurooncol. 2010 Jan;96(1):103-14. Epub 2009 Dec 3.)
 * Anticonvulsants; 2010 PMID 19957015 -- "The role of prophylactic anticonvulsants in the management of brain metastases: a systematic review and evidence-based clinical practice guideline." (Mikkelsen T, J Neurooncol. 2010 Jan;96(1):97-102. Epub 2009 Dec 3.)
 * Surgery; 2010 PMID 19960230 -- "The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline." (Kalkanis SN, J Neurooncol. 2010 Jan;96(1):33-43. Epub 2009 Dec 4.)
 * WBRT; 2010 PMID 19960231 -- "The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline." (Gaspar LE, J Neurooncol. 2010 Jan;96(1):17-32. Epub 2009 Dec 4.)
 * SRS; 2010 PMID 19960227 -- "The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline." (Linskey ME, J Neurooncol. 2010 Jan;96(1):45-68. Epub 2009 Dec 4.)
 * Chemotherapy; 2010 PMID 19960229 -- "The role of chemotherapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline." (Mehta MP, J Neurooncol. 2010 Jan;96(1):71-83. Epub 2009 Dec 4. Review.)
 * Retreatment; 2010 PMID 19957016 -- "The role of retreatment in the management of recurrent/progressive brain metastases: a systematic review and evidence-based clinical practice guideline." (Ammirati M, J Neurooncol. 2010 Jan;96(1):85-96. Epub 2009 Dec 3.)
 * Investigational therapies; 2010 PMID 19957013 -- "The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics." (Olson JJ, J Neurooncol. 2010 Jan;96(1):115-42. Epub 2009 Dec 3.)

American Society for Radiation Oncology (ASTRO)
 * 2012 No PMID yet  -- "Radiotherapeutic and surgical management for newly diagnosed brain metastasis/es: An American Society for Radiation Oncology evidence-based guideline (2012)" (Tsao M, Practical Radiation Oncology 2012 -- online before print)
 * 2005 (Review) - PMID 16111570 &mdash; "The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for brain metastases." Mehta MP et al. Int J Radiat Oncol Biol Phys. 2005 Sep 1;63(1):37-46.

Cancer Care Ontario
 * Single Brain Metastasis
 * Management of Brain Metastases
 * 2005 PMID 15807895 Full text -- "Clinical practice guideline on the optimal radiotherapeutic management of brain metastases." (Tsao MN, BMC Cancer. 2005 Apr 4;5:34.)

European Federation of Neurological Societies (EFNS)
 * Diagnosis and Treatment of Brain Metastases
 * 2006 PMID 16834697 -- "EFNS Guidelines on diagnosis and treatment of brain metastases: report of an EFNS Task Force." (Soffietti R, Eur J Neurol. 2006 Jul;13(7):674-81.)

International RadioSurgery Association (IRSA)
 * Stereotactic Radiosurgery for Patients with Metastatic Brain Tumors (2008)

German Society of Radiation Oncology (DEGRO)
 * Brain Metastases and Leptomeningeal Carcinomatosis (2010) PMID 20127222 -- "DEGRO Practical Guidelines for Palliative Radiotherapy of Breast Cancer Patients: Brain Metastases and Leptomeningeal Carcinomatosis." (Feyer P, Strahlenther Onkol. 2010 Feb;186(2):63-69. Epub 2010 Jan 26.)
 * Conclusion: RT is an effective tool for palliative treatment of brain metastases and leptomeningeal carcinomatosis

Driving Restrictions:
 * Neurosurgical Society of Australasia (NSA)
 * Brain Tumors and Driving: A guide for patients and carers
 * Brain Tumors and Driving: A guide for clinicians
 * See also: NSWOG - NSW (New South Wales) Oncology Working Group: Neuro-oncology link