Radiation Oncology/NHL/CNS Metastases

Lymphoma Metastatic to the Central Nervous System

Outcomes

 * MDACC, 1998 - PMID 9454747 -- "Risk factors, treatment, and outcome of central nervous system recurrence in adults with intermediate-grade and immunoblastic lymphoma." (Van Besien K, Blood. 1998 Feb 15;91(4):1178-84.)
 * Incidence of CNS recurrence 4.5% at 1 year from primary lymphoma treatment. Risk factors for CNS recurrence: elevated LDH, multiple extranodal sites.
 * 24 pts developed CNS recurrence. Median survival 88 days. 1 yr OS 25.3%. RT provided symptomatic relief in 6 of 9.