Radiation Oncology/Cancer Syndromes/Cockayne Syndrome

Cockayne Syndrome


 * wikipedia entry
 * Emedicine entry
 * DNA Repair chapter


 * Mutations in ERCC6 and ERCC8, part of the NER pathway for single strand DNA damage repair
 * Autosomal recessive syndrome
 * Growth failure, impaired development of CNS, photosensitivity, premature aging
 * No cancer predisposition