Radiation Oncology/Benign/Peyronie's Disease

Peyronie's disease

 * Saarland, 2006 (Germany) (1983-2000) PMID 16169684 &mdash; "Results of radiotherapy for Peyronie's disease." (Niewald M, Int J Radiat Oncol Biol Phys. 2006 Jan 1;64(1):258-62.)
 * Retrospective. 101/154 patients. Penis deviation 30-50 degrees. 1-2 indurated foci. Pain in 48/92 patients. RT 30 - 36 Gy at 2 Gy/fx. Mean F/U 5 years
 * Outcomes: Improved deviation in 47%, reduction in number of foci in 32%, reduction in size of foci in 49%, less induration 52%. Pain relief 5%
 * Toxicity: Mild dermatitis 28%, mild urethritis 4%
 * Conclusion: RT effective therapy option