Handbook of Genetic Counseling/Lhermitte-Duclos disease

Lhermitte-Duclos disease (LDD):


 * associated with Cowden syndrome.
 * dysplastic gangliocytoma (hamartoma) of the cerebellum.
 * sporadic, familial.
 * PTEN mutations.
 * all patients with LDD should be counselled as in Cowden syndrome.